American Journal of Clinical Neurology and Neurosurgery
Articles Information
American Journal of Clinical Neurology and Neurosurgery, Vol.1, No.1, Jul. 2015, Pub. Date: Jul. 11, 2015
Guillain-Barre Syndrome Associated With Acute Hepatitis A Infection
Pages: 10-12 Views: 1920 Downloads: 1187
Authors
[01] Samir Patel, Department of Neurology, Sir Ganga Ram Hospital, New Delhi, India.
[02] Ish Anand, Department of Neurology, Sir Ganga Ram Hospital, New Delhi, India.
[03] Anuradha Batra, Department of Neurology, Sir Ganga Ram Hospital, New Delhi, India.
[04] Pooja Gupta, Department of Neurology, Sir Ganga Ram Hospital, New Delhi, India.
[05] Rajat Agrawal, Department of Neurology, Sir Ganga Ram Hospital, New Delhi, India.
Abstract
Guillain-Barre syndrome is an acute polyradiculoneuropathy, often triggered by a preceding bacterial or viral infection. Campylobacter jejuni, mycoplasma pneumoniae, cytomegalovirus and Epstein–Barr virus are the common triggering agents. Infectious agents induced molecular mimicry is supposed to be involved in the pathogenesis of GBS. Rarely, it has been observed in association with hepatotropic viruses (Hepatitis A, B, C and E). However, the nature of the shared epitopes has not been characterized in hepatotropic viruses. We report a case of Guillain-Barre syndrome following acute hepatitis A in a young Indian female.
Keywords
Guillain-Barre Syndrome, Hepatitis A
References
[01] Nobuhiro Y. Guillain–Barré syndrome and anti-ganglioside antibodies: a clinician-scientist’s journey. Proc Jpn Acad Ser B. Phys Biol Sci. 2012; 88: 299–326.
[02] Nobuhiro Y., Hartung HP. Guillain–Barré Syndrome. N Engl J. Med 2012;366:294-304.
[03] Nobuhiro Y. Infectious origins of, and molecular mimicry in, Guillain-Barre and Fisher syndromes. Lancet Infect Dis 2001;1:29–37.
[04] Grygorczuk S., Zajkowska J., Kondrusik M., Pancewicz S., Hermanowska-Szpakowicz T. Guillain-Barré Syndrome and its association with infectious factors. Neurol Neurochir Pol 2005; 39: 230-236.
[05] Jacobs BC, Rothbarth PH, van der Meché FG, Herbrink P, Schmitz PI, de Klerk MA, et al. The spectrum of antecedent infections in Guillain‑Barre syndrome: A case‑control study. Neurology 1998; 51: 1110‑15.
[06] Asbury AK, Arnason BG, Adams RD. The inflammatory lesion in idiopathic polyneuritis: its role in pathogenesis. Medicine (Baltimore) 1969;48: 173-215.
[07] Kaida K., Sonoo M., Ogawa G, Kamakura K., Ueda-Sada M., Arita M., et al. GM1/GalNAc-GD1a complex: a target for pure motor Guillain-Barre syndrome. Neurology 2008;71: 1683-1690
[08] Dimachkie MM, Barohn RJ. Guillain-Barré Syndrome and Variants. Neurol Clin. 2013; 31: 491–510.
[09] Stübgen JP. Neuromuscular complications of hepatitis A virus infection and vaccines. J Neurol Sci. 2011;300:2–8.
[10] Menon D., Jagtap SA, Muralidharan D. Guillain-Barré syndrome following acute viral hepatitis A. J. Neurosci Rural Pract. 2014; 5: 204–205.
600 ATLANTIC AVE, BOSTON,
MA 02210, USA
+001-6179630233
AIS is an academia-oriented and non-commercial institute aiming at providing users with a way to quickly and easily get the academic and scientific information.
Copyright © 2014 - American Institute of Science except certain content provided by third parties.