[01] Shohreh Malek Khosravi, Gynecology Department Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran. [02] Farid Arman, Gynecology Department Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran. [03] Hania Shakeri, Gynecology Department Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Background: Ectopic pregnancy is one of the major life threatening conditions during the first trimester of pregnancy. EP increases the risk of maternal mortality and morbidity. The prevalence of Ectopic Pregnancy is about 2% in the developed world. Objective: This observational descriptive cross-sectional study was performed to determine the frequency of surgery in 70 patients who were diagnosed with Ectopic Pregnancy in their first trimester after failed treatment with single or multiple dose of methotrexate (MTX). Materials and methods: In this observational descriptive cross-sectional survey, 70 patients with Ectopic Pregnancy referring to Imam Reza Hospital (affiliated to Kermanshah university of Medical sciences) between years 2008-2010 who received single or multiple dose of methotrexate as primary management were evaluated. Results: The results demonstrated that surgery was required in 16 patients (22.9%). The contraceptive method was effective in determining the probability of requiring surgery after treatment with Methotrexate among these patients (P=0.035) and the most common methods were IUD (100%) and TL (35.7%). Conclusions: Totally, according to the obtained findings, it may be concluded that need to surgery in patients with Ectopic Pregnancy is a multifactorial entity.

Ectopic Pregnancy, Methotrexate, MTX

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