Clinical Medicine Journal
Articles Information
Clinical Medicine Journal, Vol.1, No.2, Jun. 2015, Pub. Date: May 6, 2015
Primary Endobronchial Carcinoid Tumour: Case Report and Review of Literature
Pages: 43-47 Views: 1947 Downloads: 884
[01] Archana Kumari, Department of Radiodiagnosis, Delhi State Cancer Institutes, Dilshad Garden, Delhi, India.
[02] Pankaj Sharma, Department of Radiodiagnosis, Delhi State Cancer Institutes, Dilshad Garden, Delhi, India.
[03] Gargi Tikku, Department of Pathology, Delhi State Cancer Institutes, Dilshad Garden, Delhi, India.
[04] Kriti Malhotra, Department of Radiodiagnosis, Delhi State Cancer Institutes, Dilshad Garden, Delhi, India.
Bronchial carcinoid tumours are carcinoid tumours primarily occurring in relation to a bronchus. They are uncommon comprising only 1-2% of all lung tumours. This is case of 28 year old man with persistent wheezing, cough with expectoration, fever and chest pain on left side, for four to five months. All routine investigations were within normal limits. Chest roentgenogram demonstrated partial volume loss on left side. Contrast Enhanced Computed Tomography (CT) of thorax revealed lobulated intraluminal mass lesion completely occluding left main bronchus; approximately 1 cm from carina. On arterial phase of the scan, the lesion showed intense homogenous enhancement characteristic of carcinoid tumours. In addition, CT scan showed mediastinal lymphadenopathy and partial left lung collapse with multiple air filled cavities. Subsequent bronchoscopy revealed reddish lobulated tumour of let main bronchus. Bronchoscopy alveolar lavage (BAL) showed no abnormal cells. On Bronchoscopy biopsy, it came out to be typical carcinoid tumour of grade 1 type. Patient was initially unsuccessfully treated for bronchial asthma, as intrabronchial mass was not suspected. Further investigations revealed intrabronchial mass lesion completely occluding left main bronchus. This intrabronchial mass in our case was carcinoid tumour. Thus, due to lack of characteristic symptoms, diagnosis of intrabronchial carcinoid is usually delayed. We advocate that patient with refractory respiratory symptoms should undergo comprehensive Radiological and Pathological investigations for accurate and early diagnosis.
Endobronchial Carcinoids, Computed Tomography, Bronchoscopy, Radiotherapy
[01] Colby TV, Koss MN, Travis WD. Carcinoid and other neuroendocrine tumors. In: Colby TV, Koss MN, Travis WD, eds. Atlas of tumorpathology: tumors of the lower respiratory tract, fasc 13, ser 3. Washington, DC: Armed Forces Institute of Pathology, 1995; 287–317.
[02] Paladugu RR, Benfield JR, Pak HY, Ross RK, TeplitzRL. BronchopulmonaryKulchitzky cell carcinoma: a new classification scheme for typical and atypical carcinoids. Cancer 1985; 55:1303–1311.
[03] Godwin JD II. Carcinoid tumors: an analysis of 2837 cases. Cancer 1975; 36:560–569.
[04] Buck JL, SobinLH. Carcinoids of the gastrointestinal tract. RadioGraphics 1990; 10:1081–1095.
[05] Fraser RG, Pare´ JAP, Pare´ PD, Fraser RS, Genereux GP. Neoplasms of pulmonary neuroendocrine cells. In: Fraser RG, Pare´ JAP, Pare´ PD, Fraser RS, Genereux GP, eds. Diagnosis of diseases of the chest. 3rd ed. Philadelphia, Pa: Saunders,1991; 1476–1497.
[06] Kulke MH, Mayer RJ. Carcinoid tumours. N Engl J Med. 1999;340:858–868 (doi: 10.1056/NEJM199903183401107).
[07] Dusmet ME, McKneally MF. Pulmonary and thymic carcinoid tumors. World J Surg 1996; 20: 189–195.
[08] Horton KM, Fishman EK. Cushing syndrome due to a pulmonary carcinoid tumor: multimodality imaging and diagnosis. J Comput Assist Tomogr 1998; 22:804–806.
[09] Rosado de Christenson ML, Abbott GF, KirejczykWM, Galvin JR, Travis WD. Thoracic carcinoids: radiologic-pathologic correlation. RadioGraphics 1999; 19:707–736.
[10] Hage R, de la Rivière AB, Seldenrijk CA, Bosch JMM van den. Update in pulmonary carcinoid tumours: a review article. Ann SurgOncol. 2003;10: 697–704 (doi: 10.1245/ASO.2003.09.019).
[11] Nessi R, Basso Ricci P, Basso Ricci S, BoscoM,Blanc M, Uslenghi C. Bronchial carcinoid tumors: radiologic observations in 49 cases. J ThoracImaging1991; 6:47–53.
[12] Magid D, Siegelman SS, Eggleston JC, FishmanEK, Zerhouni EA. Pulmonary carcinoid tumors: CT assessment. J Comput Assist Tomogr 1989; 13:244–247.
[13] Naidich DP. CT/MR correlation in the evaluation of tracheobronchial neoplasia. RadiolClin North Am 1990; 28:555–571.
[14] AronchickJM, Wexler JA, Christen B, Miller W, Epstein D, Gefter WB. Computed tomography of bronchial carcinoid. J Comput Assist Tomogr 1986; 10:71–74.
[15] AvecillasJF, Mehta AC. Flexible bronchoscopy and the use of lasers. In: Wang KP, Mehta AC, Turner JF, editors. FlexibleBronchoscopy. 2nd edition. Massachesselts: Blackwell Publishing, 2005; 157-173.
MA 02210, USA
AIS is an academia-oriented and non-commercial institute aiming at providing users with a way to quickly and easily get the academic and scientific information.
Copyright © 2014 - 2017 American Institute of Science except certain content provided by third parties.