[01] Yagoub Hamadt Allah Elhaj Abd Elseed, Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Albaha University, Al-Baha, Saudi Arabia. [02] Mohamed A. E. M. Ibrahim, Faculty of Applied Medical Sciences, Albaha University, Al-Baha, Saudi Arabia. [03] Waled Amen Mohammed Ahmed, Nursing Department, Faculty of Applied Medical Sciences, Albaha University, Al-Baha, Saudi Arabia.

The cancer is usually minimizing the immunity, which make the patients with cancers at risk for many microbial infections and even septicaemia. This study was done to identify and isolate aerobic bacterial septicaemic pathogens among cancer patients. This study was performed in Radiation and Isotopes national Centre of Khartoum Hospital (previously Alzarra) during the period of May to July 2013. Thirty two blood samples were collected from cancer patients suspected to septicemia. All samples were initially inoculated in brain heart infusion broth and diphasic brain heart infusion. The study showed that eleven (34%) of this samples were showed growth, while twenty one (66%) showed no growth. After subculture on Blood agar, MacConky agar and Chocolate agar, all isolated pathogens were subjected to essential bacteriological biochemical tests and identified as Staphylococcus aureus N= 9 (72.7%), Klebsiella pneumoniae N= 2 (18.2%), and Bacillus species N=1 (9.1%). Septicaemia in patients with cancer was mainly caused by Staphylococcus aureus and it commonly in patients using chemotherapy.

Septicaemia, Cancer, Pathogens, Isolation, Bacteria

[01] Forbes, B.A; Sahm, D.F; and Weisseld, A. S. Bailey and Scott S diagnostic microbiology, 12th edition. 2007. 881-892. [02] Munford RS, Suffredini AF. Sepsis, severe sepsis, and septic shock. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Churchill Livingstone Elsevier; chap. 2009. 70. [03] Greenwood, D; Slack, R; Peutherer, J; and Barer, M. Medical microbiology. 17th edition. 2007. 663-664. [04] William, R; and George, J. Gram positive septicaemia in deplitated patients. Archives of international medicine; 1962. 110(6):847-855. [05] Moran, J; Atwood, R; and Rowe, M. A Clinical and bacteriologic study of infection Associated with venus cutdowns. Clinical infectious disease. North England Journal of Medicine; 1992. 18(272):554–560. [06] Barrow G. I. and Feltham R. K. Cowan and Steel’s manual for the identification of medical bacteria, 3rd, ed., Cambridge university press. 1993. [07] Bailey and Scott’s Diagnostic microbiology: A textbook for isolation and identification of pathogenic microorganisms. Edited by Forbes BA, Sahm DF, Weissfeld AS. St. Louis: The Mosby Company; 2002:378-422. [08] Diekma DJ, Beekman SE, Chapin KC, Morel KA, Munson E, Deorn GV: Epidemiology and outcome of nosocomial and community onset bloodstream infection. J Clin Microbiol 2003, 41:3655-3660. [09] Aiker AM, Mturi N, Niugana P: Risk and cause of paediatrics hospital acquired bactermia Klifi district hospital, Kenya: prospective cohort study. Lancet J 2011, 10(Suppl 37):2012-2017. [10] Zenebe T, Kannan S, Yilma D, Beyene G: Invasive Bacterial Pathogens and their antibiotic susceptibility patterns in Jimma University specialized Hospital, Jimma, South West Ethiopia. Ethiop J Health Sci 20011, 21(Suppl 1):1-8. [11] Ali J, Kebede Y: Frequency of isolation and antimicrobial susceptibility pattern of bacterial isolation from blood culture in Gondar University Hospital. Ethio Med J 2008, 46(2):155-161. [12] Kardos, G. Isoproterenol in the treatment of shock due to bacteremia with gram-negative pathogens. North Eng J Med; 1966. 21; 274(16):868–873. [13] Weil, M; Shubin, H; and Bildde, M. Septicaemia caused by gram negative microorganisms. Analysis of 169 cases. American journal of medicine; 1993. 8(8), 479–483. [14] Shitaye D, Asrat D, Woldeamanuel Y, Worku B: Risk factors and etiology of neonatal sepsis in Tikur Anbessa University Hospital, Ethiopia. Ethiop Med J 2010, 48(Suppl 1):11-21. [15] Wilson GS, Miles A, Topley W. Principal of bacteriology, virology and immunology.6th ed. Edward Arnold 1975; 847.