International Journal of Biomedical and Clinical Sciences
Articles Information
International Journal of Biomedical and Clinical Sciences, Vol.3, No.2, May 2018, Pub. Date: Feb. 5, 2018
Impact of Opioid-Induced Constipation on Opioid Therapy Among Patients with Cancer: A Review
Pages: 22-26 Views: 52 Downloads: 29
Authors
[01] Mohammed Tuffaha, Oncology Unit, Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates.
[02] Nezar Ahmed Salim, Oncology Unit, Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates.
[03] Hasan Abu Nigim, Oncology Unit, Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates.
[04] Mohammed Eid Al Khodary, Oncology Unit, Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates.
Abstract
Constipation is a common problem as a result of medication (in particular opioids) for pain control, as well as disease, dietary and mobility factors, Opioids are very effective analgesics, frequently prescribed in cancer pain, despite proven analgesic efficacy, the use of opioids is commonly associated with frequently dose-limiting constipation that seriously impacts on patients’ quality of life, almost all patients on opioids report constipation as the major side-effect. Therefore this article provides an integrative review about opioid –induced constipation from all aspects with focus on the prevention. Methods: An online search of science direct data base and PubMed and Google scholar. Based on the inclusion criteria 7 articles were selected and formed the basis for this review. Conclusion: Prevention of opioid- induced constipation, in general, is considered to be a more effective strategy than merely treating it when it occurs, It is widely advised that laxatives should be started concurrently with opioids, prevention of opioid induced constipation could lead to clinical and economic benefits, Effective prevention and treatment of opioid-induced constipation can improve pain management and quality of life for patients and their families; However, limited RCTs to determine the effectiveness of prophylactic management on the prevention of opioid-induced constipation.
Keywords
Opioid-Induced Constipation, Impact, Cancer, Prevention, Management
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