International Journal of Biomedical and Clinical Sciences
Articles Information
International Journal of Biomedical and Clinical Sciences, Vol.5, No.1, Mar. 2020, Pub. Date: Feb. 24, 2020
Overview of Erythrocyturia Pattern Among Eastern Sudanese Patients: A Study of the Diagnostic Pathway
Pages: 41-49 Views: 1097 Downloads: 211
Authors
[01] Bashir Abdrhman Bashir, Hematology Department, Faculty of Medical Laboratory Sciences, Port Sudan Ahlia College, Port Sudan, Sudan.
[02] Maisa Ahmed Badneen, Clinical Chemistry Department, Port Sudan Hospital for Surgery & Hemodialysis, Ministry of Health, Red Sea State, Sudan.
[03] Mohammed Omer Gibreel, Hematology Department, Faculty of Medical Laboratory Sciences, Port Sudan Ahlia College, Port Sudan, Sudan.
Abstract
Background: Hematuria is a prevalent finding encountered during manual routine urine examination in the laboratory. Two principle characters can be watched, microscopic and macroscopic hematuria. It tends to be clear for genuine urological conditions. Dysmorphic red blood cells (dRBCs) in urine deposit may be a successful incentive in the diagnosis of the glomerular and non-glomerular origin of hematuria. A cross-sectional observational study was enlisted to assess the capacity of dRBCs to perceive glomerular inception from another kidney hindrance. Methods: We have appraised 170 consecutive patients with hematuria at Dr. Awaad Medical Center, Red Sea State, Sudan from June 2017 to July 2018. Renal ultrasonography and urinalysis were performed. The statistical statements were analyzed using SPSS version 24.0 for windows. Results: Roughly 10/170 (5.9%) had gross hematuria, 49/170 (28.8%) had microscopic hematuria with clinical symptoms, 56/170 (32.9%) had microscopic hematuria with proteinuria, and 55/170 (32.4%) had isolated hematuria. The causes of hematuria were highlighted as (72.9% non-glomerular and 19.5% glomerular). dRBCs were encountered in 122/170 (71.8%) (P = 0.000) of an entire group of patients with hematuria. fRBCs were also detected in 99/170 (58.2%) of patients (P = 0.000) of an entire group of patients with hematuria. Of 170 patients, 50 (29.4%) had > 16.6 dRBCs and 47 (27.6%) had ≥ 12.0 fRBCs. dRBCs was sensitive (66.7%), specific (68.8%), with a positive predictive value (90.2%) for glomerular disease. Hematuria outcomes expressed as urinary tract infection (UTI) in (37.6%), followed by glomerulonephritis (19.5%), cystitis (18.2%), pyelonephritis (10.0%), and renal stones (7.6%). Conclusion: Urinary dRBCs > 16.6 in Urine sediment test was an extensive prognostic for glomerular illness, however, in joined with proteinuria it is explicit characteristic of the glomerular starting point. fRBCs were revealed to the non-glomerular origin. Dysmorphic RBCs persist in healthy subjects denotes a glomerular source. UTI, glomerulonephritis, and cystitis were considered the prevalent outcomes of hematuria in this report.
Keywords
Hematuria, dRBCs, Glomerular Disease, Albuminuria, Port Sudan
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