International Journal of Chemical and Biomolecular Science
Articles Information
International Journal of Chemical and Biomolecular Science, Vol.1, No.2, Aug. 2015, Pub. Date: Jul. 23, 2015
Study on Toxicity of Clove Eugenia caryophllata Water Extract on Wister Albino Rats
Pages: 69-73 Views: 3756 Downloads: 938
Authors
[01] Marwa Izzeldeen, Department of Biochemistry, Faculty of Veterinary Medicine, University of Khartoum, Khartoum, North-Sudan.
[02] Mohammed Abdelkreim, Department of Range Science, College of Forestry and Range Science, Sudan University of Science and Technology (SUST), Khartoum, Sudan.
Abstract
Eugenia caryophllata is a plant which is believed by Sudanese herbalists to have antimicrobial, antiseptic and anesthetic effect. This plant has been tested in the present study to investigate its toxic effect in twenty Wister albino rats. The plant was extracted with water as a solvent. Distilled water was used to extract the polar compounds. In this study twenty Wister albino rats were divided into four groups (A, B, C, D) each consisted of five rats 100 ml of distilled water was added to 20 g of clove. Group A: was kept as a control in which rats were given distilled water only (the solvent). Group B: was given a dose of 10 drops of the clove water extract. Group C: was given a dose of 20 drops of the clove water extract. Group D: was given a dose of 30 drops of clove water extract. Bilirubin, ALT, AST and ALP enzymes were the parameters which were measured among the three groups B, C, D compared with the control in group (A). According to the statistic analysis there were no significant differences between the three treatments (B, C, D) and the control (A). In the present study Eugenia caryophllata (clove) was found to be non-toxic. More investigations on Eygenia caryphllata (clove) toxicity may support this study. It was concluded that Eugenia caryophllata water extract was administrated to rats, and rats were killed when the experiment was terminated after three weeks, no postmortem change were observed in any organ of treated or control rats.
Keywords
Clove Toxicity, Eygenia caryphllata, Water Extract
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