International Journal of Materials Chemistry and Physics
Articles Information
International Journal of Materials Chemistry and Physics, Vol.6, No.2, Jun. 2020, Pub. Date: Jun. 29, 2020
Preparation of Chitosan Nanoparticles from Crab Shell and Their Characterization
Pages: 23-29 Views: 670 Downloads: 388
[01] Oluwatosin Emmanuel Daramola, Department of Chemistry, Federal University of Technology Akure, Akure, Nigeria.
[02] Oluwaseun Adekoya Adelaja, Department of Chemistry, Federal University of Technology Akure, Akure, Nigeria.
Preparation and characterization of Chitosan nanoparticles (CHNP) is presented with the aim of determining the particle size and morphology, surface chemistry, thermal stability through a simple and cost effective process of production preparation. CHNP were prepared through drop wise addition of sodium tripolyphosphate solution to chitosan solutions in the ratio of 1: 1 under stirring. Chitosan gave a yield of 61% from the crab shell and a degree of deacetylation (DOD) of 75%. The low DOD could be responsible for the high yield of chitosan which is due to the incompletely removed acetyl groups in chitin. The final weight of the chitosan was observed to have increased after the conversion to nanoparticles, and this could be as a result of the crosslinking of the chitosan and the TPP. The nanoparticle size was determined with UV-Visible spectrometer showing a characteristics maximum adsorption of 0.056 at 230 nm and the XRD characterization showed two characteristics peaks at 2θ = 16° and 23°. The ionotropic gelation method used in this study was an effective and simple method in achieving reproducible nanoparticles with the desired safety and physicochemical characteristics. Due to their nano particle size, the produced CHNP could find application in pharmaceutical industries for drug delivery and repair of tissue. Also, in wastewater treatment, CHNP could find application because of its tendency to adsorb toxic dyes and metals as well as a filler for non-degradable polymers.
Chitosan, Nanoparticles, Nanotechnology, Deacetylation, Ionic Gelation, Pharmaceutical
[01] Megha A, Mukesh KA, NS, Sarika P, Ritu D, Priyanka G (2018) Preparation of CHNP and their In-vitro Characterization. Int J Life Sci Scienti Re 4 (2): 1713-1720. DOI: 10.21276/ijlssr.2018.4.2.17.
[02] Fernandez KSO (2004) Physicochemical and functional properties of crawfish chitosan as affected by different processing protocols. Dissertation Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA.
[03] Tharanathan RN (2003) Biodegradable films and composite coatings: past, present and future. Trends in Food Science and Technology 14: 71-78.
[04] Shahidi F, Abuzaytoun R (2005) Chitin, chitosan, and co products: chemistry, production, applications, and health effects. Advance Food Nutrition Res 49: 93-135.
[05] Olajide A, Okoronkwo AE, Oluwasina OO, Abe TO (2018) Utilization of blue crab shells for the synthesis of CHNP and their characterization. Songklanakarin J Sci Technol 40 (5): 1043-1047.
[06] Defelice RC, Eldredge LG, Carlton VT (2001) Non indigenous invertebrates. In LG Eldredge and C. Smith (Eds.), Guidebook to the introduced marine species in Hawaiian waters. Bishop Museum Technical Report 21: 217-274.
[07] Aranaz I, Mengibar M, Harris R, Panos I, Miralles B, Acosta N, Heras A (2009) Functional characterization of chitin and chitosan. Current Chemical Biology 3: 203-230.
[08] Ting DR, Shen Y (2005) Antibacterial finishing with chitosan derivatives and their Nanoparticles. Dyeing Finishing 14: 12–14.
[09] Shi XY, Tan TW (2003) Preparation of chitosan/ethylcellulose complex microcapsule and its application in controlled release of vitamin D2. Biomaterials 23: 4469–4473.
[10] Yeşim SA, Başak G (2017) Removal of Methyl Red, a cationic dye, Acid Blue 113, an anionic dye, from wastewaters using chitin and chitosan: influence of copper ions. Desalination and Water Treatment 73: 289–300.
[11] Domsy JD, Roberts GAF (1985) Evaluation of infrared spectroscopic techniques for analyzing chitosan. Macromolecular Chemistry, 186, 1671.
[12] Maram THAK, Mohammed R, Maher ZE (2013) Wastewater treatment with chitosan nano-particles. International Journal of Nanotechnology and Application 3 (2): 39-50.
[13] Kumirska J, Czerwicka M, Kaczyński Z, Bychowska A, Brzozowski K, Thöming J, Stepnowski P (2010) Application of Spectroscopic Methods for Structural Analysis of Chitin and Chitosan. J Mar Drugs 8: 1567-1636.
[14] Deleanu C, Simonescu CM., Nechifor G (2014). Re-moval of Cu(II) and Ni(II) Ions from aqueous solution using chitosan and chemical modified chitosan Abdel Fattah WI, Jiang T, El Bassyouni GE, Laureuci CT (2007) Synthesis, characterization of chitosans and fabrication of sintered chitosan micro-sphere matrices for bone tissue engineering. Acta Biomaterialia 3 (4): 503-514.
[15] Sadeghi AMM, Amini M, Avadi MR, Siedi F, Rafiee TM, Junginger HE (2008) Synthesis, characterization and antibacterial effects of trimethylated and triethylated 6NH2 6Deoxy Chitosan. Journal of Bioactive and Compatible Polymer 23: 262-275.
[16] Krishnaveni B, Priya P (2014) Green synthesis and antimicrobial activity of silver nanoparticles from Calotropis gigantea, Catharanthus roseus, Chitin and Chitosan. Int. J. Chemical Studies 1: 2321-2490.
[17] Liu CG, Desai KGH, Chen XG, Park HJ, (2005) Preparation and characterization of nanoparticles containing trypsin based on hydrophobically modified chitosan. J Agric Food Chem 53: 1728-1733.
[18] Abdel-Fattah WI, Jiang T, El Bassyouni GE, Laureuci CT (2007) Synthesis, characterization of chito-sans and fabrication of sintered chitosan micro-sphere matrices for bone tissue engineering. Acta Biomaterialia, 3 (4), 503 514.
[19] Anand M, Kalaivani R, Maruthupandy M, Kumaraguru AK, Suresh S (2014) Extraction and characterization of chitosan from marine crab and squilla collected from the Gulf of Mannar Region, South India. J Chitin Chitosan Sci 2 (16): 280-287.
[20] Jaworska M, Kula K, Chassary P, Guibal E (2003) Influence of chitosan characteristics on polymer properties: II. Platinum sorption properties. Polymer International 52 (2): 206–212.
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