International Journal of Materials Chemistry and Physics
Articles Information
International Journal of Materials Chemistry and Physics, Vol.6, No.2, Jun. 2020, Pub. Date: Jun. 29, 2020
Preparation of Chitosan Nanoparticles from Crab Shell and Their Characterization
Pages: 23-29 Views: 670 Downloads: 388
Authors
[01] Oluwatosin Emmanuel Daramola, Department of Chemistry, Federal University of Technology Akure, Akure, Nigeria.
[02] Oluwaseun Adekoya Adelaja, Department of Chemistry, Federal University of Technology Akure, Akure, Nigeria.
Abstract
Preparation and characterization of Chitosan nanoparticles (CHNP) is presented with the aim of determining the particle size and morphology, surface chemistry, thermal stability through a simple and cost effective process of production preparation. CHNP were prepared through drop wise addition of sodium tripolyphosphate solution to chitosan solutions in the ratio of 1: 1 under stirring. Chitosan gave a yield of 61% from the crab shell and a degree of deacetylation (DOD) of 75%. The low DOD could be responsible for the high yield of chitosan which is due to the incompletely removed acetyl groups in chitin. The final weight of the chitosan was observed to have increased after the conversion to nanoparticles, and this could be as a result of the crosslinking of the chitosan and the TPP. The nanoparticle size was determined with UV-Visible spectrometer showing a characteristics maximum adsorption of 0.056 at 230 nm and the XRD characterization showed two characteristics peaks at 2θ = 16° and 23°. The ionotropic gelation method used in this study was an effective and simple method in achieving reproducible nanoparticles with the desired safety and physicochemical characteristics. Due to their nano particle size, the produced CHNP could find application in pharmaceutical industries for drug delivery and repair of tissue. Also, in wastewater treatment, CHNP could find application because of its tendency to adsorb toxic dyes and metals as well as a filler for non-degradable polymers.
Keywords
Chitosan, Nanoparticles, Nanotechnology, Deacetylation, Ionic Gelation, Pharmaceutical
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