American Journal of Food Science and Health
Articles Information
American Journal of Food Science and Health, Vol.2, No.4, Aug. 2016, Pub. Date: Jul. 27, 2016
Serum Levels of Zinc and Copper Elements in Children Diagnosed with Intestinal Parasitic Infection in Hive Hospital, Duhok City / Kurdistan Region in Iraq
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[01] Mhommed Adnan Ibrahim, College of Science, University of Duhok, Duhok, Iraq.
[02] Husni Abdulla Mhammad, College of Science, University of Duhok, Duhok, Iraq.
[03] Qays Lazgin Barany, College of Science, University of Duhok, Duhok, Iraq.
Zinc and copper are vital elements for growth, reproduction and development which are components of some cellular enzyme and play an important role in the stabilizing of some cellular membrane. The aim of this study was to investigate the association between intestinal parasites and serum levels of zinc and copper in children of Duhok City/Kurdistan Region in Iraq, because despite the significant recent advances in the knowledge of the molecular biology and biochemistry of E. histolytica little is known about the pathogenesis of Entamoebasis and there relation with these two elements in Duhok City. The study started from 12/2014 to 8/2015. In this study a total of 15 infested and 31 non-infested persons as a control group were selected from total 44 samples. Stool samples were collected from all cases and controls and examined for detection of cyst and/ or trophozoite of Entamoeba and Giardia from each patient with 5 ml blood sample was obtained for estimation of zinc and copper. In this study, serum zinc levels in infected children were significantly lower when compared with healthy children, it was found a decrease level in serum zinc in 50% of cyst and/ or trophozoite of Entamoeba positive group, but copper level showed no statistical significant difference in comparison with healthy children. It has been concluded that intestinal parasites affect the level of serum zinc in testes children during present study.
Zinc, Copper, Intestinal Parasites and Children
[01] Abbaspour N., Hurrell R. and Kelishadi R. (2014). Review on iron and its importance for human health. J. Res Med Sci.; 19: 164–174.
[02] Ali F. Bafghi, Mahboubehsadat S., AkbarB. and Arefeh D. Tafti. (2015). Comparison of Trace Elements of Zinc and Copper between Children with Giardiasis and Healthy International J. of Medical Laboratory; 2(3): 194-199.
[03] Azza S. El-Ghareeb, Raniyah H. M. Shaker, Ashraf M. S. Shahin, Neveen T. Abed and Ghada El Bathyony (2015). Zinc Deficiency and Gastrointestinal Parasitic Infections Among Children. International J. of Medical and Health Sciences; 4(1).
[04] Bean N. H., Goulding J. S., Lao, C. and Angulo F. J. (1996). Surveillance for food borne disease outbreaks-United states, 1988-1992. CDC Surveillance. Summaries. Morb. mortal. Weeklyrep., 45(5):1-66.
[05] Demirci M., Delibas N., Altuntas I., Oktem F. and Yonden Z. (2003). Serum iron, zinc and copper levels and lipid peroxidation in children with chronic giardisis. TJ Health Popul Nutr Mar. 21(1):72-75.
[06] Devlin TM. (2009). Text Book of Biochemistry with clinical correlations. 7th Ed. New York: Willey-Liss; p. 723-27.
[07] Ertan P., Ysereli K., Kurt O., Balcioğlu IC. and Onağ A. (2002). Serological levels of zinc, copper and iron elements among Giardia lamblia infected children in Turkey. Pediatr Int. 44(3): 286-88.
[08] Faber S., Zinn GM., Kern JC and Kingston H. M. (2009) The plasma zinc/serum copper ratio as a biomarker in children with autism spectrum disorders. Biomarkers 14: 171–180.
[09] Fabris N., Mocchegiani E. (1995). Zinc, human diseases and aging. Aging (Milano) 7: 77–93.
[10] Farthing MJ. (1997). The molecular pathogenesis of giardiasis. J Pediatr Gastroenterol Nutr. 24:79-88.
[11] Hesham M. S., Edariah, A. B. and Norhayati, M. (2004). Intestinal parasitic infections and micronutrient deficiency: a review. Med. J. Malaysia, 59: 284-293.
[12] Heyneman C. A. (1996). Zinc deficiency and taste disorders. Ann. Pharmacother 30: 186–187.
[13] IOM/FNB – Institute of Medicine, Food and Nutrition Board (2001) Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. National Academy Press, Washington, DC.
[14] Kal, K. and Chambers, R. (2008). Handbook on Community-led Total Sanitation, Plan UK Accessed 2015-2-26 Henry JR. (1984). Clinical diagnosis and Management by Laboratory Methods. Philadephia. W. B. Saunders., p. 376-378.
[15] Karakas Z., Demirel N., Tarakcioglu M. and Mete N. (2001). Serum zinc and copper levels in southeastern Turkish children with giardiasis or amebiasis. Biol Trace Elem Res.; 84: 11-8.
[16] Kim, BI., Ock, M. S., Chung, DI., Yong, t.s. and Lee, K.i. (2003). Intestinal parasite infection status of Inhabitants in the Roxas city, the Philippines Korean. G. Parasitol.
[17] Lengerich E. J., Addiss D. J. and Juranek D. (2001). Sever giardiasis in United state. Clin.Infect.Dis.; 18: 760-763.
[18] Lifschitz C. (2012). New actions for old nutrients. Acta Sci Pol Technol Aliment 11: 183–192.
[19] Mustafa D., Namik D., Irfan A., Faruk O. and Zafer Y. (2003). Serum Iron, Zinc and Copper Levels and Lipid Peroxidation in Children with Chronic Giardiasis. J. Health popul Nutr. 21(1): 72-75.
[20] Olivares JL., Fernandez R., Fleta J., Rodriguez G. and Clavel A. (2003). Serum mineral levels in children with intestinal parasitic infection. Dig Dis.; 21(3):258–61.
[21] Oteiza P. I., and Mackenzie G. G. (2005) Zinc, oxidant-triggered cell signaling, and human health. Mol Aspects Med 26: 245–255.
[22] Prasad A. S. (1995). Zinc: an overview. Nutrition 11 (1 Suppl): 93–99.
[23] Prasad A. S. (2012). Discovery of human zinc deficiency: 50 years later. J Trace Elem Med Biol 26: 66–69.
[24] Prasad A. S., Beck F. W., Grabowski SM, Kaplan J. and Mathog R. H. (1997). Zinc deficiency: changes in cytokine production and T-cell subpopulations in patients with head and neck cancer and in noncancer subjects. Proc Assoc Am Physicians 109: 68–77.
[25] Ratanapo, S., Mungthin M., Soontarapa, S., Falthed C. Sripatanapipong S. Pangsin R. Naaglor T. Pyaray P. Taamas, S. and Leelayoova S. (2008). Multiple modes of transmission of Giardiasis in primary school children of a rural community. Thailand. Am. G. Clin.Nutr.78 (4):611-615.
[26] Robertson LJ. (2000). Severgiardiasis and cryptosporidiosis in Scotland & UK. Epidemiol. Infect; 117: 551-561
[27] Samra HK., Ganguly NK., Garg UC., Goyal J. and Mahajan RC. (1988). Effect of excretory-secretory products of Giardia lamblia on glucose and phenylalanine transport in the small intestine of Swiss albino mice. Biochem Int.7: 801-12.
[28] Sandstead HH., Prasad A. S., Schulert A. R., Farid Z., Miale A. Jr., Bassilly S. and Darby W. J. (1967). Human zinc deficiency, endocrine manifestations and response to treatment. Am J Clin Nutr 20: 422–442.
[29] Tanyuksel M., Sayal A. and Aydin A. (1995). Trace element levels in some parasitic disease. Acta Parasitol Turcica. 19: 315–21.
[30] Tietz NW. (1986). Textbook of Clinical Chemistry. PhilaLielphia. \V. B. Saunders. 801-972.
[31] WHO. (2002). Burden of disease in disability adjusted life years (daily s) by cause, sex and mortality stratum in WHO regions. Geneva: WHO.
[32] Zynep K., Nureten D., Mehmet T. and Nuriye M. (2001). Serum Zinc and Copper levels in southeastern Turkish Children with Giardiasis and Amebiasis. Biological Trace element research; 84(1): 11-18.
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