American Journal of Food Science and Health
Articles Information
American Journal of Food Science and Health, Vol.1, No.3, Aug. 2015, Pub. Date: Jul. 16, 2015
The HOXD Locus in the Pathogenesis of Celiac Disease
Pages: 82-85 Views: 1341 Downloads: 364
Authors
[01] Procino Alfredo, Department of Neurosciences, Reproductive and Odontostomatologic Sciences, Medical School Federico II, Naples, Italy.
Abstract
Celiac disease (CD) is immune-mediated enteropathy that occurs in genetically predisposed subjects following ingestion of an alcohol-soluble component of gluten, gliadin, found in some cereals (wheat, barley, rye, spelled, etc.). HOX, are 39 transcription factors mostly involved in the regulation of embryonic development and regulates the cell memory program through the interaction with non coding RNA. I have already titled this network as “The Rosetta stone” of human biology; therefore, does HOX network able to control change in the cell memory program during CD?
Keywords
Celiac Disease, Homeobox, lncRNA, HOTAIR
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